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Richard H Aster Selected Research

Thrombocytopenia (Thrombopenia)

1/2021A prospective, blinded study of a PF4-dependent assay for HIT diagnosis.
1/2021Characterization of glycoprotein IIb/IIIa-specific alloantibodies induced by cross-strain platelet immunization in mice.
9/2020Moxifloxacin-Induced Thrombocytopenia Mediated by Moxifloxacin-Dependent IgM and IgG Antiplatelet Antibodies: A Case Report.
1/2020Recapitulation of posttransfusion purpura by cross-strain platelet immunization in mice.
10/2019Regulatory T Cells Control PF4/Heparin Antibody Production in Mice.
5/2018Disease burden, complication rates, and health-care costs of heparin-induced thrombocytopenia in the USA: a population-based study.
1/2018Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies.
10/2017A Platelet Factor 4-Dependent Platelet Activation Assay Facilitates Early Detection of Pathogenic Heparin-Induced Thrombocytopenia Antibodies.
1/2017IVIg for Treatment of Severe Refractory Heparin-Induced Thrombocytopenia.
1/2016A Novel PF4-Dependent Platelet Activation Assay Identifies Patients Likely to Have Heparin-Induced Thrombocytopenia/Thrombosis.
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Richard H Aster Research Topics

Disease

45Thrombocytopenia (Thrombopenia)
01/2021 - 01/2002
17Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2021 - 02/2003
11Neonatal Alloimmune Thrombocytopenia
11/2019 - 08/2004
9Hemorrhage
09/2020 - 08/2004
8Thrombosis (Thrombus)
05/2018 - 10/2006
4Transfusion-Related Acute Lung Injury
12/2014 - 10/2011
3Transfusion Reaction
01/2021 - 09/2002
3Neutropenia
04/2019 - 07/2004
3Neoplasms (Cancer)
03/2014 - 03/2006
3Cytopenia
01/2009 - 04/2005
2Wounds and Injuries (Trauma)
05/2018 - 06/2012
2Thrombotic Thrombocytopenic Purpura
05/2015 - 01/2002
2Colonic Neoplasms (Colon Cancer)
03/2014 - 03/2006
2Hemolytic Anemia
10/2010 - 01/2002
2Sepsis (Septicemia)
01/2010 - 07/2004
1Drug Hypersensitivity (Drug Allergy)
09/2020
1Melena
09/2020
1Exanthema (Rash)
09/2020
1Epistaxis (Nosebleed)
09/2020
1Immune System Diseases (Immune Disorders)
10/2019
1Periodontal Diseases (Periodontal Disease)
05/2018
1Thromboembolism
01/2017
1Hemophilia A (Haemophilia)
12/2016
1Thrombotic Microangiopathies
05/2015
1Hemolytic-Uremic Syndrome
05/2015
1Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
03/2015
1Evans Syndrome
03/2015
1Hemoperitoneum
01/2015
1Purpura
01/2015
1Infections
06/2012

Drug/Important Bio-Agent (IBA)

36AntibodiesIBA
09/2020 - 03/2002
25Pharmaceutical PreparationsIBA
09/2020 - 03/2002
16Heparin (Liquaemin)FDA LinkGeneric
01/2021 - 01/2003
8Platelet Membrane GlycoproteinsIBA
11/2019 - 03/2006
7Platelet Factor 4IBA
10/2019 - 09/2011
6Isoantigens (Alloantigen)IBA
01/2020 - 08/2004
6Quinine (Quinson)FDA Link
10/2015 - 02/2003
4IntegrinsIBA
01/2021 - 06/2012
4Anti-Bacterial Agents (Antibiotics)IBA
09/2020 - 07/2004
4Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2018 - 03/2006
4Integrin beta3 (GPIIIa)IBA
06/2015 - 02/2003
4Human Platelet AntigensIBA
05/2014 - 08/2004
4AntigensIBA
05/2012 - 03/2010
4Eptifibatide (Integrilin)FDA Link
03/2009 - 09/2002
4Glycoproteins (Glycoprotein)IBA
10/2006 - 09/2002
3IsoantibodiesIBA
01/2021 - 08/2004
3Immunoglobulin G (IgG)IBA
09/2020 - 03/2002
3Member 2 Protein Solute Carrier Family 44IBA
12/2014 - 03/2010
3LigandsIBA
06/2012 - 09/2002
2Intravenous Immunoglobulins (IVIG)FDA Link
09/2020 - 01/2017
2AutoantibodiesIBA
01/2020 - 07/2004
2Antigen-Antibody Complex (Immune Complex)IBA
10/2019 - 02/2014
2Serotonin (5 Hydroxytryptamine)IBA
10/2017 - 10/2013
2Fibrinolytic Agents (Antithrombotic Agents)IBA
02/2016 - 01/2009
2Monoclonal AntibodiesIBA
10/2015 - 10/2015
2EpitopesIBA
10/2015 - 10/2011
2thiamine triphosphorate (TTP)IBA
05/2015 - 01/2002
2Platinum Compounds (Compounds, Platinum)IBA
03/2014 - 03/2010
2Platelet Membrane Glycoprotein IIbIBA
01/2009 - 10/2006
2Abciximab (ReoPro)FDA Link
01/2009 - 03/2002
2Tirofiban (Aggrastat)FDA Link
01/2009 - 09/2002
2orbofibanIBA
10/2006 - 12/2002
1Proton Pump InhibitorsIBA
09/2020
1Moxifloxacin (Avelox)FDA Link
09/2020
1Immunoglobulin M (IgM)IBA
09/2020
1Adrenal Cortex Hormones (Corticosteroids)IBA
09/2020
1beta-LactamsIBA
04/2019
1AnticoagulantsIBA
01/2017
1Factor VIII (Coagulation Factor VIII)IBA
12/2016
1Hemostatics (Antihemorrhagics)IBA
02/2016
1ProdrugsIBA
02/2016
1Plasminogen Activators (Plasminogen Activator)IBA
02/2016
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
02/2016
1didodecyldimethylammoniumIBA
10/2015
1Polyethylene (Polythene)IBA
03/2015
1Cefazolin (Ancef)FDA LinkGeneric
01/2015
1Irinotecan (Camptosar)FDA LinkGeneric
02/2014
1FucoseIBA
01/2014
1OligosaccharidesIBA
01/2014
1Protamines (Protamine Sulfate)FDA Link
10/2013
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
06/2012
1Biological ProductsIBA
06/2012
1LipidsIBA
06/2012
1Biomarkers (Surrogate Marker)IBA
06/2012
1Deoxyribonucleases (DNase)FDA Link
06/2012
1Arginine (L-Arginine)FDA Link
05/2012
1Glutamine (L-Glutamine)FDA Link
05/2012
1DNA (Deoxyribonucleic Acid)IBA
05/2012

Therapy/Procedure

4Therapeutics
09/2020 - 01/2017
2Platelet Transfusion (Blood Platelet Transfusions)
09/2020 - 09/2002
2Drug Therapy (Chemotherapy)
03/2014 - 03/2006
2Aftercare (After-Treatment)
10/2013 - 09/2002
1Blood Transfusion (Blood Transfusions)
01/2020
1Arthroplasty
05/2018
1Surgical Amputation (Amputations)
05/2018
1Knee Replacement Arthroplasty (Total Knee Replacement)
05/2018
1Length of Stay
05/2018
1Cardiopulmonary Bypass (Heart-Lung Bypass)
05/2018
1Intrauterine Devices (Intrauterine Device)
03/2015
1Antibiotic Prophylaxis
01/2015